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Molecular Imaging: PET-CT

How PET-CT and molecular imaging detect, stage and monitor cancer, including PSMA and DOTATATE scans.

How PET-CT Works

A small amount of radioactive tracer is injected; cancer cells that take up more tracer glow on the PET image, while CT adds anatomical detail. The combined scan shows both where and how active a tumor is.

Common Tracers

TracerUsed for
FDGMost cancers — lymphoma, lung, melanoma, head & neck
PSMA (Ga-68 / F-18)Prostate cancer staging and recurrence
DOTATATENeuroendocrine tumors
Fluoroestradiol (FES)ER-positive breast cancer

Preparing for Your Scan

  • Fast for 4–6 hours for FDG scans
  • Tell staff if you are diabetic, pregnant or breastfeeding
  • Avoid strenuous exercise the day before
  • Plan for 2–3 hours at the imaging center

Theranostics

The same targets used for imaging can deliver radiation therapy — for example Lu-177 PSMA therapy for prostate cancer and Lu-177 DOTATATE for neuroendocrine tumors.

Medically reviewed content for education only — not a substitute for advice from your oncology team.