FOLFIRINOX

Leucovorin, 5-Fluorouracil, Irinotecan, Oxaliplatin · Tri-chemotherapy Gastrointestinal Protocol

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Indications & Uses

First-line treatment for Metastatic and Locally Advanced Pancreatic Adenocarcinoma, and advanced Colorectal Cancer.

Contraindications

Poor performance status (ECOG > 1), significant baseline cardiac or hepatic failure.

Side Effects & Warnings

Severe neutropenia, peripheral sensory neuropathy, severe diarrhea, fatigue, thrombocytopenia.

Drug & Dietary Interactions

Extensive interactions; consult specific multi-agent administration and hydration protocols.

For educational and informational purposes only. Do not alter medication doses or regimens without consulting your licensed oncology physician or care team.

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