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ONC-ORG

FOLFIRI

Leucovorin, 5-Fluorouracil, Irinotecan · Colorectal & Gastrointestinal Regimen

Indications & Uses

First-line and second-line therapy for Metastatic Colorectal Cancer, Gastric Cancer, and Esophageal Adenocarcinoma.

Contraindications

Known homozygous DPD deficiency, severe active inflammatory bowel disease.

Side Effects & Warnings

Early and late diarrhea, cholinergic syndrome, neutropenia, mucositis, fatigue.

Drug & Dietary Interactions

Extensive interactions; consult specific multi-agent administration and hydration protocols.

For educational and informational purposes only. Do not alter medication doses or regimens without consulting your licensed oncology physician or care team.

Patient & Caregiver Support

Ask About This Medication

Connect with an ONC-ORG counselor regarding drug access, copay relief, patient assistance programs, or related clinical trials.