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ONC-ORG

Keytruda

pembrolizumab · PD-1 Checkpoint Inhibitor

Indications & Uses

First-line and adjuvant treatment of melanoma, non-small cell lung cancer (NSCLC), head and neck squamous cell carcinoma, classical Hodgkin lymphoma, urothelial carcinoma, microsatellite instability-high (MSI-H) solid tumors, triple-negative breast cancer (TNBC), and cervical cancer.

Contraindications

Known severe hypersensitivity to pembrolizumab or any of the excipients in the formulation.

Side Effects & Warnings

Fatigue, musculoskeletal pain, decreased appetite, pruritus, diarrhea, nausea, rash, fever, cough, dyspnea, and immune-mediated adverse reactions including pneumonitis, colitis, hepatitis, and endocrinopathies.

Drug & Dietary Interactions

Concomitant use of systemic corticosteroids or immunosuppressants before starting Keytruda may diminish clinical activity; however, systemic steroids may be used to treat immune-mediated adverse reactions.

Regulatory & Prescribing Information

FDA Approved Biologic (BLA 125514). Full Prescribing Information and Medication Guide available.

For educational and informational purposes only. Do not alter medication doses or regimens without consulting your licensed oncology physician or care team.

Patient & Caregiver Support

Ask About This Medication

Connect with an ONC-ORG counselor regarding drug access, copay relief, patient assistance programs, or related clinical trials.